So - in Australia, we have a number of red outbreaks in remote areas.
Some of these are over 1000km from the nearest agent and would cost a lot to get to and remove, (driving, fuel/flights, accommodation etc).
Now - I'm all for this infection, its been super interesting and fun doing science on them.
But. If we need to continually travel huge distances to remove these, and if they spread to inaccessible mine sites*/BGAN areas etc, they will become a massive issue. No agent here is going to make multiple trips like that just to k ill them.
*For information - Western Australia has a lot of mines, these often have portals. Usually only staff and contractors have intermittent access to them, but if the mine closes, the areas basically inaccessible to anyone. They are mostly out in the middle of the desert, huge distances apart.
Also - Russia & Belarus - redfections should be removed from this region. Nobody will be able to link across the area at current spread rates and nobody can do anything about them,
Anyway - hopefully Niantic have already thought of these things and they won't be an issue.